Indole alkaloids from Aspidosperma rigidum and A. schultesii and their antiparasitic effects.

نویسندگان

  • Matías Reina
  • Wilfredo Ruiz-Mesia
  • Lastenia Ruiz-Mesia
  • Rafael Martínez-Díaz
  • Azucena González-Coloma
چکیده

Five oxindole alkaloids, three plumerane-type alkaloids, subtype haplophitine, and one aspidospermatane-type alkaloid, subtype tubotaiwine, were isolated from the medicinal plants Aspidosperma rigidum and A. schultesii. One compound was identified as the transoid conformer of 18-oxo-O-methylaspidoalbine which was not previously described. The antiparasitic activity of all compounds against Trypanosoma cruzi and Leishmania infantum and their non-specific cytotoxicity against mammalian cells were also determined.

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عنوان ژورنال:
  • Zeitschrift fur Naturforschung. C, Journal of biosciences

دوره 66 5-6  شماره 

صفحات  -

تاریخ انتشار 2011